HIGHLIGHTS
SUMMARY
Mutations and an overabundance of α-Syn have been shown to cause synaptic malfunctions in a dose-dependent manner (Nemani et_al, 2010; Logan et_al, 2017; Bridi and Hirth, 2018). Stimulus-independent, intrinsic neuronal network activity (abbreviated "network activity" or "network bursts" throughout the text) is manifested in several large network clusters of the human brain, such as the default mode network, the salience network, or the visual networks (van den Heuvel et_al, 2009; Havlik, 2017). Disruption of this type of endogenous activity is associated with deficiencies of cognition and other symptoms in neurodegenerative or psychiatric . . .
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