Α -synuclein transgenic drosophila as a model of parkinson’s disease and related synucleinopathies

HIGHLIGHTS

  • who: Hideya Mizuno and collaborators from the School of Pharmaceutical Sciences, Women's University, Nishinomiya, Hyogo, Japan have published the article: α -Synuclein Transgenic Drosophila As a Model of Parkinson’s Disease and Related Synucleinopathies, in the Journal: (JOURNAL)
  • what: The authors will discuss what has been revealed in the pathogenesis of synucleinopathies using α-Syn Drosophila models, focusing on "misfolding and aggregation of α-Syn", "posttranslational modifications of α-Syn", and "oxidative stress" .

SUMMARY

    Protein inclusions known as Lewy Bodies (LBs) are one of the hallmarks of Parkinson's disease (PD), in which the . . .

     

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