Α1a adrenergic receptor induces eukaryotic initiation factor 4e-binding protein 1 phosphorylation via a ca2+-dependent pathway independent of phosphatidylinositol 3-kinase/akt*

HIGHLIGHTS

• who: Igor I. Rybkin from the (UNIVERSITY) have published the article: α1A Adrenergic Receptor Induces Eukaryotic Initiation Factor 4E-binding Protein 1 Phosphorylation via a Ca2+-dependent Pathway Independent of Phosphatidylinositol 3-kinase/Akt*, in the Journal: (JOURNAL) of November/24,/1999
• what: This study investigated the effect of a Gq-coupled receptor on protein synthesis and the phosphorylation state and function of 4E-BP1 in Rat-1 fibroblasts expressing the human ␣1A adrenergic receptor. The authors show here that stimulation of the ␣1A AR leads to an increase in protein synthesis accompanied by phosphorylation . . .
  

   

  

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