Β-escin overcomes trastuzumab resistance in her2-positive breast cancer by targeting cancer stem-like features

HIGHLIGHTS

• who: Soeun Park from the All animal procedures were conducted according to the Guide for the Care and Use of Laboratory Animals, with the approval of Korea University Institutional Animal Care and Use Committee (IACUC, KOREA-2021-0070)Female BALB/c nude mice (, weeks old) were purchased from NARA Biotech (Seoul, Korea) and kept in a specific pathogen-free environment. , cells (, u00d7 u00ad106) were inserted into the fourth mammary fat pads of the BALB/c nude female mice after one-week acclimation (n=8/each group). When average tumor volumes reached , u00admm3, test animals were randomized into . . .
  

   

  

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