HIGHLIGHTS
- who: Spectroscopy et al. from the Department of Protein Engineering, Genentech Inc, DNA Way, South San Francisco, CA, USA have published the research: β -hairpin polypeptides by design and selection, in the Journal: (JOURNAL)
- what: Throughout this work, the authors have placed a strong emphasis on using NMR spectroscopy to characterize the peptides being studied. The preference for Phe is expected from the studies described above (Fig 2) since this residue is at the NHB site.
SUMMARY
Although prevalent in folded proteins, designing short peptides that adopt a β-hairpin conformation using only . . .
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