new personalized genetic mouse model of lesch-nyhan syndrome for pharmacology and gene therapy

HIGHLIGHTS

  • who: Vladislav A. Kalmykov from the Institute of Gene Biology of the Russian Academy of Sciences, Vavilova str, Moscow, Russia University of the Russian Ministry of Health, Ostrovityanova str, Moscow, Russia have published the paper: New personalized genetic mouse model of Lesch-Nyhan syndrome for pharmacology and gene therapy, in the Journal: (JOURNAL)
  • what: In this paper, we presented the results of the development and production of a new genetically modified mouse line model for Lesch-Nyhan syndrome.
  • how: Developing a system for gene editing To introduce the 8Val deletion in the first . . .

     

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