efficiency evaluation of amlodipine combined with n-acetylcysteine on indomethacin-induced gastritis in rats

HIGHLIGHTS

  • who: Yara Annouf from the Damascus University, Faculty of Pharmacy, Mazzeh, Damascus, Syria have published the research: Efficiency evaluation of Amlodipine combined with N-acetylcysteine on Indomethacin-induced gastritis in rats, in the Journal: (JOURNAL)
  • what: The major reason for gastric pathogenesis caused by NSAIDs including INDO is reduced prostaglandin (PG) synthesis by inhibition of the cyclooxygenases (COXs) (Yadav et_al 2012).
  • how: The results showed that macroscopic stomach damage scores caused by administration of Indomethacin did not significantly decrease by administration of N-acetylcysteine alone (p>0.05) but it decreased significantly by . . .

     

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