0-0 subject section predicting the pathogenicity of missense variants using features derived from alphafold2

HIGHLIGHTS

• who: Bioinformatics and collaborators from the of Human Genetics, Bonn School of Medicine, University Hospital of Bonn, University of Bonn, Bonn, Lu00fcbeck, Lu00fcbeck, Germany have published the article: 0-0 Subject Section Predicting the pathogenicity of missense variants using features derived from AlphaFold2, in the Journal: (JOURNAL)
• what: The aim of this study was to determine whether the structure predictions of AlphaFold2 can improve systematic prediction of the pathogenicity of missense variants. Using variants from DMS and ClinVar, the authors show that AlphaFold2 structures contain additional information that is beneficial for pathogenicity assessment, and that . . .
  

   

  

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