:1 cellular heterogeneity in prolactin transcription 59-69 calcium dynamics and chromatin remodelling underlie heterogeneity in prolactin transcription

HIGHLIGHTS

• who: Endocrinology et al. from the of Biology, Hill University, Ormskirk, Lancashire, UK have published the article: :1 Cellular heterogeneity in prolactin transcription 59-69 Calcium dynamics and chromatin remodelling underlie heterogeneity in prolactin transcription, in the Journal: (JOURNAL)
• what: The authors focus on two factors that may contribute to the transcriptional heterogeneity of prolactin seen within populations of pituitary cells; calcium dynamics and histone modification. The authors show that within a clonal population of resting GH3 cells there is variability in the extent of prolactin expression, calcium dynamics and histone acetylation.
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