1-methyltryptophan treatment ameliorates high-fat diet-induced depression in mice through reversing changes in perineuronal nets

HIGHLIGHTS

  • What: Due to the exploratory nature of this study, no formal power analysis or sample size estimation was conducted, and the sample size estimation was based on prior experience and literature .
  • Who: Juntao Hu from the Animals and dietary intervention C BL/ JRj male mice (8-week-old) were housed in four per cage in a constant-temperature room with a , h/, h light/dark cycle and provided with free access to food and waterFollowing a, week habituation period, mice were randomly assigned to different groups to receive either a chow diet (CD, containing, % fat . . .

     

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