1h nmr signals from urine excreted protein are a source of bias in probabilistic quotient normalization

HIGHLIGHTS

• who: Gonu00e7alo D. S. Correia et al. from the (UNIVERSITY) have published the article: 1H NMR Signals from Urine Excreted Protein Are a Source of Bias in Probabilistic Quotient Normalization, in the Journal: (JOURNAL) of January/27,/2022
• what: The approach can also be effectively reversed, removing the sharp small_molecule-derived signals and providing an enhanced protein baseline for the purposes of urinary protein quantification covary systematically with factors other than the sample dilution . The authors compared the PQN coefficients obtained from the standard onedimensional (1D) 1H NMR spectra and their SMolESY processed counterparts . The . . .
  

   

  

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