HIGHLIGHTS
- who: Sara Bolivar-Wagers and collaborators from the Division University of Minnesota, Minneapolis, Minnesota, USA have published the research work: 2 3, in the Journal: (JOURNAL)
- what: The authors show that hCAR19 Tregs given with Tcons suppress aGVHD and tumor growth throughout the duration of the transplants , in stark contrast to mice treated with Tcons alone and Tcons with tEGFR Tregs.
- how: To test the hypothesis the authors developed a mouse model that replicated allo-HSCT for CD19+ B-cell malignancies. The Xenogen IVIS imaging system was used and data was analyzed using . . .
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