HIGHLIGHTS
- who: Yuen and Peter (NIH/NIDDK) [E] from the (NIDDK), National Institutes of Health (NIH), Bethesda, Maryland, USA have published the research work: 2 3, in the Journal: (JOURNAL)
- what: BAM15 administration either before or 6-12 hours after induction of sepsis decreased mortality in a clinically relevant animal model of abdominal sepsis that manifests bacteremia, unstable hemodynamics, and a high mortality despite treatment with volume resuscitation and broad-spectrum antibiotics.
- future: Extensive further study outside the scope of this paper would be needed to unravel how BAM15 alters neutrophil function(s). Studies . . .
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