2-hydroxy-4-methylbenzoic anhydride inhibits neuroinflammation in cellular and experimental animal models of parkinson’s disease

HIGHLIGHTS

  • who: Soo-Yeol Song and collaborators from the Department of Molecular Science and Technology, Ajou University, Suwon, Korea have published the research work: 2-Hydroxy-4-Methylbenzoic Anhydride Inhibits Neuroinflammation in Cellular and Experimental Animal Models of Parkinson’s Disease, in the Journal: (JOURNAL)
  • what: This study investigated the inhibitory effects of_(HMA) a novel synthetic derivative of HTB (3-hydroxy-4-trifluoromethylbenzoic acid) on neuroinflammation and underlying mechanisms activated microglia vitro and an vivo mouse model of Parkinson's disease (PD). vitro studies revealed that HMA significantly inhibited lipopolysaccharide (LPS)-stimulated excessive release of . . .

     

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