2,4-diacetylphloroglucinol reduces beta-amyloid production and secretion by regulating adam10 and intracellular trafficking in cellular and animal models of alzheimer’s disease

HIGHLIGHTS

• who: Bong-Geum Jang and colleagues from the Institute of Epilepsy Research, College of Medicine, Hallym University, Chuncheon, Korea have published the research: 2,4-Diacetylphloroglucinol Reduces Beta-Amyloid Production and Secretion by Regulating ADAM10 and Intracellular Trafficking in Cellular and Animal Models of Alzheimer’s Disease, in the Journal: Cells 2022, 2585 of /2022/
• what: Although 3 of 24 DAPG might not cross the blood-brain barrier (BBB), this study shows the potential of DAPG or derivatives as therapeutic components against AD. This study shows that DAPG, a low-molecular-weight phloroglucinol derivative, decreased . . .
  

   

  

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