24(s)-saringosterol prevents cognitive decline in a mouse model for alzheimer’s disease

HIGHLIGHTS

• who: Nikita Martens et al. from the Department of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Division Translational Neuroscience, Maastricht University, Maastricht, The Netherlands have published the research work: 24(S)-Saringosterol Prevents Cognitive Decline in a Mouse Model for Alzheimer’s Disease, in the Journal: (JOURNAL)
• what: The authors show that the phytosterol 24(S)-saringosterol prevented cognitive decline in APPswePS1∆E9 mice, despite having no effect on Aβ plaque load. The authors examined whether purified 24(S)-saringosterol can preserve cognition and prevent the development of neuropathology in a mouse . . .
  

   

  

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