3-oxo-c12:2-hsl, quorum sensing molecule from human intestinal microbiota, inhibits pro-inflammatory pathways in immune cells via bitter taste receptors

HIGHLIGHTS

• who: Garance Coquant from the Centre de Recherche Saint-Antoine, Paris, FrancePSL University have published the Article: 3-oxo-C12:2-HSL, quorum sensing molecule from human intestinal microbiota, inhibits pro-inflammatory pathways in immune cells via bitter taste receptors, in the Journal: Microbiome Medicine (PaCeMM) FHU, APHP, Paris, Ileu2011deu2011France, France. 3EPHE,
• what: The authors demonstrate that 3-oxo-C12:2-HSL exerts anti-inflammatory effects on immune cells by preventing JAK-STAT pathway activation and by activating bitter taste signalling (Fig 5). The authors show that the intestinal unsaturated 3-oxo-C12:2-HSL . . .
  

   

  

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