HIGHLIGHTS
- who: mcphee from the (UNIVERSITY) have published the research: 327-333 http://www.mdpi.org Marseille CEDEX France., in the Journal: (JOURNAL)
- what: The authors report herein a new synthesis starting from a preformed thiazolium salts.
SUMMARY
So far the reported synthetic routes leading to thiazol benzimidazole skeleton begin from the preformed 2-mercaptobenzimidazole which is condensed at the mercapto-group with various electrophiles such as alpha-haloketones, propargyl halides or 1,2,3-tribromopropane followed by cyclization to form the thiazole ring in the last step (Scheme 1). Scheme 2 . . .
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