3dpolys-le: an accessible simulation framework to model the interplay between chromatin and loop extrusion

HIGHLIGHTS

  • who: Bioinformatics et al. from the Cell Fate and Nuclear Organization, Institute of Cell Biology, University of Bern, Bern, Switzerland and Laboratoire de Biologie have published the article: 3DPolyS-LE: an accessible simulation framework to model the interplay between chromatin and loop extrusion, in the Journal: (JOURNAL) of 10/Nov/2022
  • what: V hypothesis on TAD formation for their system of interest, the authors provide an open-access, user-friendly, generic modeling framework for physics-based polymer simulations of loop extrusion (3DPolyS-LE), wrapped as a Python package, allowing users to run simulations, varying parameters . . .

     

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