HIGHLIGHTS
- who: Prisca Lagardu00e8re and collaborators from the Institut des Biomolu00e9cules Max Mousseron, CNRS, Universitu00e9 de Montpellier, ENSCM, France have published the research work: 4-Substituted Thieno[3,2-d]pyrimidines as Dual-Stage Antiplasmodial Derivatives, in the Journal: Pharmaceuticals 2022, 15, 820. of 26/06/2022
- what: We have prepared a new library of 28 thienopyrimidines, based on the structure of a first antiplasmodial hit named Gamhepathiopine (compound 1), identified to be active notably on all stages of P. falciparum.
- how: To bring chemical diversity in thienopyrimidine position 4 of the thienopyrimidine influence . . .
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