5-ala is a potent lactate dehydrogenase inhibitor but not a substrate: implications for cell glycolysis and new avenues in 5-ala-mediated anticancer action

HIGHLIGHTS

• who: Mantas Grigalavicius and collaborators from the Department of Radiation Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway , Aghia Paraskevi, Greece have published the paper: 5-ALA Is a Potent Lactate Dehydrogenase Inhibitor but Not a Substrate: Implications for Cell Glycolysis and New Avenues in 5-ALA-Mediated Anticancer Action, in the Journal: (JOURNAL)
• what: In the present PpIX synthesis in cancer cells. study, the authors examine the efficacy of 5-ALA as a glycolysis inhibitor and the consequences on The authors demonstrate the ability of 5-ALA to inhibit LDH in a . . .
  

   

  

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