5-azacytidine-mediated modulation of the immune microenvironment in murine acute myeloid leukemia

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  • who: Nancy D. Ebelt and Edwin R. Manuel from the Department of Immuno-Oncology, Beckman Research Institute of the City of Hope, Duarte, CA, USA have published the article: 5-Azacytidine-Mediated Modulation of the Immune Microenvironment in Murine Acute Myeloid Leukemia, in the Journal: Cancers 2023, 15, 118. of 21/Nov/2022
  • what: The authors describe syngeneic leukemias that are responsive to the HMA (5-Aza) as determined by augmented expression of a transduced luciferase reporter. The authors show that 5-Aza treatment rescued expression of an antigenic transgene (firefly luciferase, Fluc) in_vitro and . . .

     

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