5-demethylnobiletin mediates cell cycle arrest and apoptosis via the erk1/2/akt/stat3 signaling pathways in glioblastoma cells

HIGHLIGHTS

  • who: Xuehua Zhang from the Parul University, India have published the Article: 5-Demethylnobiletin mediates cell cycle arrest and apoptosis via the ERK1/2/AKT/STAT3 signaling pathways in glioblastoma cells, in the Journal: (JOURNAL)
  • what: In the study , the antitumor effects and potential mechanisms underlying the impact of 5-DMN on GBM were investigated for the first time both in_vitro and in_vivo. The study showed that 5-DMN could inhibit the migratory and invasive potential of cultured three different GBM cells. This study demonstrated that 5-DMN could inhibit cell proliferation, induce apoptosis in . . .

     

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