HIGHLIGHTS
- who: Terezia Prikrylova from the Institute of Medical Microbiology, Oslo University Hospital, Rikshospitalet, Norway Department of Molecular have published the research work: 5-hydroxymethylcytosine Marks Mammalian Origins Acting as a Barrier to Replication, in the Journal: Scientific Reports Scientific Reports of 15/07/2019
- what: The authors show that (5hmC) is present at mammalian replication origins. The authors show that 5hmC level is inversely proportional to proliferation; indeed 5hmC negatively influences cell division by increasing time a cell resides in G1. Later the authors propose that TET2 enzyme catalyzing 5mC to 5hmC conversion acts as . . .
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