5’isomir-183-5p|+2 elicits tumor suppressor activity in a negative feedback loop with e2f1

HIGHLIGHTS

• who: Xiaoya Li from the Division of Molecular Genome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld, Heidelberg, Germany have published the Article: 5u2019isomiR-183-5p|+2 elicits tumor suppressor activity in a negative feedback loop with E2F1, in the Journal: (JOURNAL)
• what: The authors focused on 5`isomiRs, neglecting the specific 3` end of a miRNA molecule to reduce the complexity of the system and to focus on seed-specific effects. Due to the substantial intrinsic differences between breast cancer subtypes, the authors focus here specifically on TNBC for mechanistic studies. The authors . . .
  

   

  

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