7,3⠲,4⠲-trihydroxyisoflavone, a metabolite of the soy isoflavone daidzein, suppresses ultraviolet b-induced skin cancer by targeting cot and mkk4*

HIGHLIGHTS

• who: Dong Eun Lee from the tumors was recorded weekly, with a tumor defined as an outgrowth of ⬎, mm in diameter that persisted for , weeks or moreTumor incidence, multiplicity, and volume were recorded every week until the end of the experiment at the, th week. In Vivo Western Blot Analysis-For in vivo Western blotting, mice received a topical application of, ⬘, ⬘-THIF (, or , nmol) in , ␮l acetone on their backs , h before UVB irradiation. To isolate protein from mouse skin, the dorsal skin of each mouse was excised and placed on ice. Any fat was removed, and . . .
  

   

  

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