7,8-dihydroxyflavone induces mitochondrial apoptosis and down-regulates the expression of ganglioside gd3 in malignant melanoma cells

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  • who: Won Seok Ju from the , Cell culture The SK-, and , human malignant melanoma cell lines were obtained from the Korean Cell Line Bank (Seoul, Korea). SK-, and , cells were maintained in Dulbecco`s modified Eagle`s medium (DMEM have published the paper: 7,8-Dihydroxyflavone induces mitochondrial apoptosis and down-regulates the expression of ganglioside GD3 in malignant melanoma cells, in the Journal: (JOURNAL)
  • what: In the present study, the decrease in mitochondrial membrane potential and changes in the expression of mitochondrial apoptosis pathway-related proteins clearly showed the anti-melanoma ability of 7 . . .

     

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