8-oxoguanine: from oxidative damage to epigenetic and epitranscriptional modification

HIGHLIGHTS

• who: Ja Young Hahm from the (UNIVERSITY) have published the Article: 8-Oxoguanine: from oxidative damage to epigenetic and epitranscriptional modification, in the Journal: (JOURNAL) of 21/Oct/2022
• what: This study showed that 8-oxo-dG predominantly occurs within gene deserts in correlation with lamina-associated domains (LADs), suggesting that the genome in the nuclear periphery might be spatially prone to oxidative damage.
• future: Studies are needed to determine the relationship between noncoding RNAs and o8G modification. Although the effect of 8-oxo-dG on DNA methylation may depend on the different . . .
  

   

  

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