HIGHLIGHTS
- who: Alexey V. Glukhov and Rajan Sah from the Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, France have published the paper: Electrophysiological and Molecular Mechanisms of Sinoatrial Node Mechanosensitivity, in the Journal: (JOURNAL)
- what: Specifically, the authors focus on canonical mechanoactivated channels (Piezo, TREK, and BK), slow mechanoresponsive ion_channels (including volume-regulated chloride channels (ClC), and transient receptor potential (TRP) channels), and the components of mechanochemical signal_transduction, including reactive oxygen species (ROS), cyclic adenosine monophosphate (cAMP), and inositol trisphosphate (IP3 ). The authors show the expression profile of . . .
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