Acute myeloid leukemia mutations: therapeutic implications

HIGHLIGHTS

  • who: Cristina Papayannidis et al. from the (UNIVERSITY) have published the paper: Acute Myeloid Leukemia Mutations: Therapeutic Implications, in the Journal: (JOURNAL)
  • what: AML is a complex disease with a complex genetic landscape.
  • how: Both preclinical and clinical data showed that the compound is highly active on D835-FLT3-mutated patients underlying a potentially relevant role of the drug after other FLT3 inhibitor failures.
  • future: In the near future hopefully the application of deep molecular approaches may help physicians in the identification of the personal oncogenic signature of every single patient . . .

     

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