Reversine inhibits colon carcinoma cell migration by targeting jnk1

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  • who: Reversine inhibits Colon Carcinoma et al. from the (UNIVERSITY) have published the article: Reversine inhibits Colon Carcinoma Cell Migration by Targeting JNK1, in the Journal: (JOURNAL) of 20/Nov/2017
  • what: The aim of this test was to discover potent anti-migratory agent/s (≥50% as a cut off) without any major cell toxicity (≤30% of toxicity as limit) (Fig S1). The authors report the identification of the small_molecules Reversine and SP600125, which can interfere with JNK signaling, as inhibitors of migration and metastasis of colon carcinoma cells. The authors could also show that . . .

     

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