O-glcnacylation-inducing treatments inhibit estrogen receptor α expression and confer resistance to 4-oh- tamoxifen in human breast cancer-derived mcf-7 cells

HIGHLIGHTS

• who: Shahzina Kanwal and collaborators from the Institut Cochin, Université Paris Descartes, CNRS (UMR8104), Paris, France, INSERM, Paris, France have published the article: O-GlcNAcylation-Inducing Treatments Inhibit Estrogen Receptor α Expression and Confer Resistance to 4-OH- Tamoxifen in Human Breast Cancer-Derived MCF-7 Cells, in the Journal: PLOS ONE | www.plosone.org of July/11,/2013
• what: The authors demonstrate that increasing O-GlcNAcylation results in important protective effects against tamoxifen-induced cell death in the MCF-7 cell line.
• how: The results indicated that O-GlcNAcylation-inducing treatment reduced the . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.