HIGHLIGHTS
- who: Romain Volmer from the Institut National de Recherche Agronomique (INRA), France University of California, Riverside have published the research work: Evaluation of the Antiviral Activity of Sephin1 Treatment and Its Consequences on eIF2α Phosphorylation in Response to Viral Infections, in the Journal: (JOURNAL)
- what: The authors provide evidence that Sephin1 exhibited antiviral effects against specific viruses belonging to various viral families.
SUMMARY
The guanabenz derivative Sephin1 was shown to increase eIF2α phosphorylation in cells stimulated with drugs causing PERK activation via the accumulation of unfolded proteins in the endoplasmic_reticulum lumen . . .
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