Brca1, brca2 and primary ovarian insufficiency

HIGHLIGHTS

  • who: Zhang Yinuo from the College, Perth, Scotland, RY have published the paper: BRCA1, BRCA2 and primary ovarian insufficiency, in the Journal: (JOURNAL)
  • what: In the review, the authors use BRCA to stand for both genes when they show similar characteristics.
  • future: Future studies investigating the knockout models to elucidate the role of the BRCAs genes in ovarian development and oocyte maturation will be interesting.

SUMMARY

    BRCA1 was first identified as a specific gene for earlyonset breast cancer and ovarian cancer susceptibility by using positional cloning methods in 1994 . . .

     

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