Genetic trajectory and immune microenvironment of lung-specific oligometastatic colorectal cancer

HIGHLIGHTS

  • who: Alessandro Ottaiano from the (UNIVERSITY) have published the Article: Genetic trajectory and immune microenvironment of lung-specific oligometastatic colorectal cancer, in the Journal: (JOURNAL)
  • what: In the present study, an a priori strict enrolment was conducted to select mCRC patients to (i) minimize any clinical and environmental interferences and_(ii) find any specific genotype-phenotype relationships. Comparing the genetic patterns to the pluri-metastatic disease the authors focused on KRAS and SMAD4.
  • how: A similar result was obtained with mutational profiles. The authors identified a quite homogeneous oligometastatic model did it represent . . .

     

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