A core extended naphtalene diimide g-quadruplex ligand potently inhibits herpes simplex virus 1 replication

HIGHLIGHTS

  • who: Sara Callegaro from the Department of Molecular Medicine, University of Padua, via Gabelli, Padua, Italy Department of have published the Article: A core extended naphtalene diimide G-quadruplex ligand potently inhibits herpes simplex virus 1 replication, in the Journal: Scientific Reports Scientific Reports of 12/01/2017
  • what: These are the most abundant cellular G4s in the infected cell: their lack of optimal recognition by the compound is likely the main reason for the observed low cellular toxicity at antiviral effective doses (Fig 5).

SUMMARY

    Since no definitive drugs have . . .

     

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