Molecular crowding defines a common origin for the warburg effect in proliferating cells and the lactate threshold in muscle physiology

HIGHLIGHTS

• who: Alexei Vazquez from the Department of Radiation Oncology, The Cancer Institute of New Jersey and UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ, USA Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA have published the research work: Molecular crowding defines a common origin for the Warburg effect in proliferating cells and the lactate threshold in muscle physiology, in the Journal: (JOURNAL) of 15/03/2011
• what: To study this issue here the authors develop a model of human central metabolism that incorporates a solvent capacity constraint of metabolic enzymes and mitochondria accounting . . .
  

   

  

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