Impact of anticancer chemotherapy on the extension of beta-lactamase spectrum: an example with kpc-type carbapenemase activity towards ceftazidime-avibactam

HIGHLIGHTS

  • who: Claire Amaris Hobson and collaborators from the UniversitéF-75019, Paris, France have published the paper: Impact of anticancer chemotherapy on the extension of beta-lactamase spectrum: an example with KPC-type carbapenemase activity towards ceftazidime-avibactam, in the Journal: Scientific Reports Scientific Reports

SUMMARY

    The culture of Enterobacter cloacae KPC-3 (RD26) and E. coli KPC-2 (RD29) with ACD modified the frequency of resistant mutants to CZA and rifampicin in a variable manner depending on the isolates and the cytotoxic molecules. Compared to the control culture without ACD, the frequency . . .

     

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