HIGHLIGHTS
- who: Skene and colleagues from the (UNIVERSITY) have published the Article: Resetting the chromatin landscape Abstract, in the Journal: (JOURNAL)
- future: A key question for future studies is whether the over expression of HIRA and/or histone H3.3 may accelerate reprogramming and increase the efficiency of iPSC generation by allowing the remodeling of transcription factor binding_sites.
SUMMARY
It also appears that iPSCs are not truly equivalent to the pluripotent embryonic stem_cell, as iPSCs display a reduced differentiation capacity that is biased to the cell lineage of origin. Such an understanding . . .
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