Degradation of naturally occurring and engineered antimicrobial peptides by proteases

HIGHLIGHTS

• who: Bernard J. Moncla et al. from the Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh, USA have published the article: Degradation of naturally occurring and engineered antimicrobial peptides by proteases, in the Journal: (JOURNAL)
• what: In these studies the authors report a simple method for the screening of AMPs for resistance to proteases.

SUMMARY

One of the approaches to curbing the spread of HIV is the development of intra-vaginal microbicides. LL-37 a cathelicidin, and LSA-5, a cathelicidin derivative, both have a broad spectrum of . . .

 



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