Electrochemical aromatic c-h hydroxylation in continuous flow

HIGHLIGHTS

  • who: Hao Long from the College Xiamen University, Xiamen, China have published the Article: Electrochemical aromatic C-H hydroxylation in continuous flow, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 22/06/2022
  • what: The authors report electrochemical hydroxylation of arenes of diverse electronic properties (electron-rich, -neutral, and -deficient) in continuous flow for the synthesis of phenols.

SUMMARY

    Electron-rich arenes failed completely33 or were inefficient even with controlled potential electrolysis34 because of overoxidation problems, the low reactivity of the intermediate arene radical cations, and self-coupling reactions leading to . . .

     

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