Deciphering the genetic links between psychological stress, autophagy, and dermatological health: insights from bioinformatics, single-cell analysis, and machine learning in psoriasis and anxiety disorders

HIGHLIGHTS

• What: The aim of this study was to explore the potential shared biological mechanisms underlying the comorbidity of psoriasis and anxiety disorders. The authors then used machine_learning algorithms to screen genes to explore potential links between psychological stress and skin disease. The study shows that the SLC7A5 gene is highly expressed in the early stages of T-cell development, and the expression level decreases over time, but is highly expressed again in the late stages of cell development. The authors employed NetworkAnalyst 3.0 (https://www.networkanalyst.ca/NetworkAnalyst/home.xhtml, accessed on 23 of 25 20 . . .
  

   

  

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