Dorsal root ganglion-derived exosomes deteriorate neuropathic pain by activating microglia via the microrna-16-5p/hectd1/hsp90 axis

HIGHLIGHTS

  • What: The authors investigated the effect of_(Exo) on microglial activation and the related mechanism. The authors examined the effects of DRGExo on spinal nerve ligation (SNL)-induced NP in mice in this study and investigated whether miR-16-5p delivered by DRG-Exo was involved in this process and the detailed mechanism.
  • Who: Yinghao Xing from the Department of Anesthesiology, Shengjing Hospital of China Medical, No36, have published the research: Dorsal root ganglion-derived exosomes deteriorate neuropathic pain by activating microglia via the microRNA-16-5p/HECTD1/HSP90 axis, in the Journal: (JOURNAL)
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