Promising effects of casearins in tumor-bearing mice and antinociceptive action against oncologic pain: molecular docking and in vivo findings

HIGHLIGHTS

• What: This study evaluated in vivo the antiproliferative actions of a fraction with casearins (FC) from Casearia sylvestris leaves against human colorectal carcinomas and antihyperalgesic effects on inflammatory- or opiate-based pain relief and oncologic pain in Sarcoma 180 (S180)-bearing mice.
• Who: Jurandy do Nascimento Silva and collaborators from the Laboratory of Experimental Cancerology (LabCancer), Department of Biophysics and Physiology, Department of Chemistry, Federal University of Piauí, Teresina, Brazil have published the article: Promising Effects of Casearins in Tumor-Bearing Mice and Antinociceptive Action against Oncologic Pain: Molecular Docking and In Vivo Findings, in . . .
  

   

  

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