HIGHLIGHTS
- who: Diana M. Dincã from the Centre Descartes University have published the research work: Myotonic dystrophy RNA toxicity alters morphology, adhesion and migration of mouse and human astrocytes, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: The authors first report defective astrocyte morphology and orientation in DMSXL brains, as well as reduced astrocyte adhesion and spreading in mouse and human cell culture model systems. The authors propose that impaired astrocyte arborization and polarity in DMSXL mice (comparable to that found in other mouse models of astrocyte dysfunction24,68), may affect the ultrastructure and maturation of . . .
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