HIGHLIGHTS
- who: Armando A Genazzani and colleagues from the University of Eastern Piedmont, Italy have published the article: From Rate-Limiting Enzyme to Therapeutic Target: The Promise of NAMPT in Neurodegenerative Diseases, in the Journal: (JOURNAL)
- what: In the present review, the authors first introduced the structure and biological functions of NAMPT, as well as the close correlation between NAMPT and neurodegenerative diseases (e_g, AD and PD).
- how: X-ray crystallography results showed that 15 isoindoline urea was partially involved in important pi-stacking interactions and hydrogen_bonding and hydrophobic_interactions.
- future: At present . . .
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