Sex differences in visceral pain and comorbidities: clinical outcomes, preclinical models, and cellular and molecular mechanisms

HIGHLIGHTS

  • What: The authors examine the preclinical and clinical evidence of sex differences in visceral pain focusing on IBS other forms of bowel dysfunction and IBS-associated comorbidities. In this review, the authors examine experimental animal models that may or may not resemble or align with the nature of the evidence of visceral pain-sexual dimorphism in humans, and discuss the experimental human bowelthat dysfunction.
  • Who: Namrata Tiwari and Liya Y. Qiao from the Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, VA, USA have published the research work: Sex Differences in . . .

     

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