Dual-color fish analyses of xenogeneic human fibroblast sheets transplanted to repair lung pleural defects in an immunocompromised rat model

HIGHLIGHTS

• What: The authors investigated the fate of human DFSs xenogenetically transplanted onto lung surfaces to seal PALs of immunocompromised rat. Against this background, in this study, the authors investigated whether fibroblasts engrafted after transplantation enter the lungs of the host. This study has shown that transplanted skin fibroblasts behave differently and are less likely to cause pulmonary fibrosis than existing pulmonary fibroblasts, which cause pulmonary fibrosis.
• Who: Masato Kanzaki et al. from the Department of Thoracic Surgery, Tokyo Women’s, Tokyo, Japan have published the Article: RESEARCH NOTE, in the Journal: (JOURNAL)

SUMMARY . . .

 

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