HIGHLIGHTS
- What: Informed consent was obtained from all subjects by the institution concerning care data exploitation for research purposes. The heart rate variability recordings were made prospectively on medical justifications for routine care while data were retrospectively re-analyzed with complementary technics for the research purposes. The study was approved by the Ethical Committee of Marseille University Hospital and was conducted in accordance with the Declaration of Helsinki. The authors aimed to provide classifying models of SSc subtypes, i.e., models that distinguish dcSSc from lcSSc clinical forms, from HRV linear and nonlinear metrics, and easy to compute . . .

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