Identification of novel dopamine d2 receptor ligands—a combined in silico/in vitro approach

HIGHLIGHTS

  • who: Lukas Zell and colleagues from the Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy, Paracelsus Medical University have published the research work: Identification of Novel Dopamine D2 Receptor Ligands—A Combined In Silico/In Vitro Approach, in the Journal: Molecules 2022, 4435 of 15/03/2021
  • what: The aim of this study was to develop and validate high-quality in silico pharmacophore XVOLs were also added to all the models to tually, enrichment factor (EF) and yield of actives (YoA) were used as optimization parameters during the evaluation process. The role of similar . . .

     

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